Precision Cellular Regeneration
Fuel Your Energy, Focus, and Longevity
Bring back the real you. Your energy should not be limited by the aging process. Peptide therapy has been clinically shown to raise growth hormones and energy levels to prime you back closer to your prime.
Peptide Therapy Can:
Increase Energy Levels & Stamina
Reduce Body Fat
Increase Libido
Increase HGH
And More!
Is Hormone Therapy Right for You?
For all information on hormone therapies, please email Dr. Steve Zakany at steve@drzakany.com.
What is Peptide Therapy?
Peptides are made from amino acids that are linked together. They can be thought of as a small protein. They have many functions in the body, including signaling and messaging. Some may act like neurotransmitters, while others may act like hormones. They bind to receptors on the cell surface and tell other cells and molecules what to do. Peptides are very specific, which makes them safe, well tolerated, and, more importantly, allows them to control and influence how our bodies react to physical exercise and diet.
As of January 2015, there were over 60 US FDA-approved peptide medications, 140 peptide drugs being evaluated in clinical trials, and 500 in preclinical development. As we age, production of essential amino acids and peptides decreases. As a result, our bodies begin to show signs of aging and cease to perform at an optimal level. Most peptide medications are administered subcutaneously but can also come in the form of transdermal creams, nasal sprays, and oral tablets.
Benefits of Peptide Treatment
Can Increase Lean Muscle Development
Can Improve Sleep Quality
Can Improve Mental Focus & Clarity
Can Increase Sex Drive and Libido
Can Reduce Abdominal Body Fat
Can Relieve Joint Pain
Can Support Immunity
Can Increase Skin Pigmentation for Tanning Aesthetics
Can Improve Energy Levels
Can Increase Recovery Time From Injury or Surgery
Can Improve Workouts, Stamina, and Recovery
Can Increase Natural HGH (Growth Hormone) and IGF-1 Production
Can Boost Healthy Levels of Growth Hormone
Am I a Good Candidate for Peptide Therapy?
After your consultation, Dr. Zakany (Dr. Z) determines if you're a good candidate for peptide therapy options and solutions. Dr. Z and his team will review all of your markers and goals to make their decision.
Comprehensive Hormone Management
At MenRegen, we have been specializing in hormone therapy, and men have for 30 years. Dr. Z works hand in hand with you to manage your hormones on a monthly basis to ensure you are living the best you, safe and with a caring professional. MenRegen offers hormone level tests, protocols, and self-administration training. Live your best life; let us manage your hormones.
Types of Peptides
5-Amino-1MQ
Brief Overview
5-amino-1MQ is an inhibitor of nicotinamide N-methyltransferase (NNMT). This particular enzyme plays an important role in cellular metabolism and energy homeostasis. In recent studies NNMT has been found to be up-regulated in white adipose tissue of mice compared to other tissues, thus, NNMT is an ideal target for anti-obesity medication. 5-amino-1MQ was found highly beneficial for selectivity against NNMT activity, without impacting any other molecule involved in the methionine or NADscavenging pathways. 5-amino-1MQ is a derivative of methylquinolinium (MQ) which promotes NNMT inhibition, cell viability, and membrane absorption.
- Reduction in body fat
- Reverse diet-induced obesity
- Increases NAD+ and SAM concentrations in fat cells
- Promotes lipolysis
- Prevents lipogenesis (fat accumulation)
- Inhibits NNMT (Nicotinamide N-methyltransferase) to enhance fat cell metabolism
- Modulates cellular energy balance
- Promotes the metabolism of fat rather than its storage in adipocytes
Amlexanox
Brief Overview
Amlexanox is an anti-inflammatory and anti-allergic compound which has traditionally been used to treat ulcers by reducing healing time and pain. It has multiple mechanisms of action such as inhibiting inflammation by inhibiting the release of histamine and leukotrienes. It has been shown to selectively inhibit TBK1 and IKK, producing reversible weight loss and improved insulin sensitivity, It is through this mechanism that it has produced substantial results in terms of reducing HbA1C levels thus increasing insulin sensitivity.
- Reduction in body fat
- Improved glucose control
- Improved insulin resistance
- Improved/normalized HbA1C
- Increases energy expenditure
- Effective in lowering blood sugar in a subset of obese patients with type 2 diabetes
AOD-9604
Brief Overview
AOD-9604 (Advanced Obesity Drug) is a synthetic peptide fragment that comprises a modified 15 amino acid region of GH with a tyrosine component to help stabilize the molecule. It was originally developed by Professor Frank Ng at Monash University in Australia, with the intent of finding an anti-obesity drug that had the fat burning effects of human growth hormone (HGH) without the muscle-building effect. Similar to GH, AOD-9604 aids weight reduction in rodent models of obesity and was originally developed for the treatment of obesity in humans. Additionally, it does not stimulate the production of IGF-1, has positive effects on the differentiation of adipose mesenchymal stem cells into bone, and was found to promote proteoglycan and collagen production in isolated bovine chondrocytes in an in vitro study. Its positive effects include promoting the repair of bone and cartilage in cases of OA.
- Promotes lipolysis without affecting blood sugar or tissue growth
- Prompts fat release from obese fat cells
- Prevents lipogenesis (fat accumulation)
- Boosts the body’s metabolism
- Less appetite stimulation
- Treatment in osteoarthritis, hypercholesterolemia, bone and cartilage repair - results favored when combined with BPC-157
BPC-157
Brief Overview
BPC-157, composed of 15 amino acids, is a partial sequence of body protection compound (BPC) that is discovered in and isolated from human gastric juice. Experimentally it has been demonstrated to accelerate the healing of many different wounds, including tendons, muscles, nervous system and superior healing of damaged ligaments. Those who suffer from discomfort due to muscle sprains, tears and damage may benefit from treatment with this peptide. It can also help aid skin burns to heal at a faster rate and increase blood flow to damaged tissues.
- Supports cognitive performance
- Supports joint health
- Protects against drug-induced damage
- Restores the serotonergic transport system
- Protects the dopaminergic system
- Enhances the GABAergic system
- Benefits for ulcers in the stomach
- Benefits for intestinal damage
- May help irritable bowel disease
- Promotes lipolysis
- Improves overall skin appearance
- Repairs skin barrier proteins
CJC-1295+IPAMORELIN
Brief Overview
CJC-1295 is a 30 amino acid peptide hormone that has shown promising and amazing results as a Growth Hormone Releasing Hormone (GHRH) analog. CJC-1295 stimulates HGH secretion and can provide a steady increase of HGH with minimal effect on cortisol and prolactin levels. This means increased protein synthesis thus promoting both growth and fat loss simultaneously. Ipamorelin mimics ghrelin and binds to the ghrelin receptor (or GH secretagogue receptor, GHSR) in the brain, thereby selectively stimulating the release of GH from the pituitary gland. This results in increased plasma GH levels, which would affect many biological processes. Unlike other GH releasing peptides, Ipamorelin only stimulates GH release in a manner very similar to that of growth hormone releasing hormone. This combination results in a great aid for sleep, energy, stamina and recovery benefits.
- Promotes lipolysis
- Improves sleep quality
- Increased energy
- Increased endurance
- Improved cellular repair
- Increased IGF-1
- Increased bone density
- Accelerated injury recovery
- Improved immune system
- Increased protein synthesis
- Increase in lean body mass
- Increased collagen production
- Less appetite stimulation
Dihexa
Brief Overview
Dihexa, also known as N-hexanoic-Tyr-Ile-(6) aminohexanoic amide, is an oligopeptide drug derived from angiotensin IV that binds with high affinity to hepatocyte growth factor (HGF) and potentiates its activity at its receptor, c-Met. Dihexa has been found to potently improve cognitive function in animal models of Alzheimer's disease-like mental impairment. In an assay of neurotrophic activity, Dihexa was found to be seven orders of magnitude more potent than brain-derived neurotrophic factor. An orally active, blood– brain barrier permeable compound was subsequently developed with the potential to treat Alzheimer’s disease and other disorders that would benefit from augmented synaptic connectivity.
- Improves cognitive function
- Helps in the treatment of Alzheimer’s Disease and Parkinson’s Disease
- Improves long and short-term memory
- Helps manage depression
- Enhances creative thinking and social interaction
- Improved heart health
- Improves brain focus
Epithalon
Brief Overview
Epithalon (also known as Epitalon) is the synthetic version of the polypeptide Epithalamin which is naturally produced in humans. The pineal peptide preparation is secreted in the epithalamium-epiphyseal region of the brain. It is used to regulate metabolism in the epiphysis, increase the sensitivity of hypothalamus to its natural hormonal influences, normalize the function of the anterior pituitary, regulate the levels of gonadotropins and melatonin in the body. Epithalamin increases a person's resistance to emotional stress and also acts as an antioxidant. It is a bio-regulator for the endocrine system, especially for the pineal gland, and has been shown to lengthen telomeres in human cells. The mechanisms in Epitalon’s primary role is to increase the natural production of telomerase, a natural enzyme that helps cells reproduce telomeres, which are the protective parts of our DNA. This allows the replication of our DNA so the body can grow new cells and rejuvenate old ones. It reduces lipid oxidation and ROS, along with normalizing T cell function. It seems to normalize cholesterol and uric acid, along with prolactin levels. It has shown promise in restoring pancreatic hormone function. Epithalon can also restore and normalize melatonin levels in older patients who have lost some pineal function due to aging.
- Regulates cell cycle through telomerase activity up-regulation
- Increases and restores telomere length
- Improves glucose tolerance and decreases insulin and triglyceride levels
- Improvement on disturbed sleeping patterns
- Activate gene expression and protein synthesis in specific target tissues
- Activates chromatin which its primary function is packaging long DNA molecules into more compact, denser structures
FGL
Brief Overview
FGL (Fibroblast Growth Loop) is a small peptide derived from the neural cell adhesion molecule (NCAM). NCAM is a glycoprotein that is found on the surface of nerve cells (neurons) and glial cells (protect neurons). NCAM activates FGL which in turn stimulates the production of new projections of developing neurons. FGL is associated in the formation of synapses between neurons which results in improved synaptic plasticity and neuronal development. Combined with enhanced synaptic transmission means FGL can help encode information, resulting in improved learning and memory. Neuronal cell protection and preservation with FGL then becomes an important peptide with the potential to treat multiple conditions affecting cognitive function.
- Improves cognitive function
- Neuroprotective benefits
- Helps in the treatment of Alzheimer’s Disease
- Improves long and short-term memory
- Helps manage anxiety & depression
- Enhances creative thinking and social interaction
- Improves brain focus & learning
GHK-CU
Brief Overview
GHK-Cu is a tripeptide with the amino acid sequence glycyl-histidyl-lysine. It naturally occurs in human plasma. It has also been found in saliva and urine. In plasma the level of GHK declines as you age. This decline in the GHK-level coincides with the noticeable decrease in regenerative capacity of an organism. GHK-Cu functions as a complex with copper stimulates collagen production, accelerates wound healing and contraction, improves the take of transplanted skin, and also possesses antiinflammatory properties.
- Improved skin elasticity and firmness
- Reduces hyper-pigmentation and skin spots
- Stimulates skin collagen
- Improves overall skin appearance
- Reduces inflammation
- Improves wound healing and reduce infections
- Increases hair growth and follicle size
- Increase production of stem cells
- Bone Repair
- Antimetastatic properties
Hexarelin
Brief Overview
Hexarelin, also referred to as Examorelin or Hexarelin Acetate, is a powerful synthetic hexapeptide and a selective agonist of the ghrelin/growth hormone secretagogue receptor. It acts as a growth hormone secretagogue, meaning it stimulates the body's natural growth hormone production by amplifying the release signal. This leads to an increased secretion of growth hormone from the pituitary gland. Hexarelin also inhibits the hormone somatostatin (growth hormone inhibiting hormone), which normally suppresses growth hormone output. By blocking somatostatin, Hexarelin boosts natural growth hormone levels, promoting lean muscle growth, accelerated fat loss, stronger tendons and ligaments, improved flexibility, and faster recovery from injuries and training.
- Promotes lipolysis
- Increased bone density
- Increase in lean body mass
- Increase muscle mass
- Improves sleep quality
- Increased energy
- Increased endurance
- Improved cellular repair
- Increased IGF-1
- Supports cognitive performance
- Enhanced collagen production
IGF-LR3
Brief Overview
IGF-LR3 is a synthetic protein and lengthened analogue of human insulin-like growth factor 1 (IGF-1). It differs from native IGF-1 in that it possesses an arginine instead of a glutamic acid at the third position in its amino acid sequence ("arginine 3"), and also has an additional 13 amino acids at its N-terminus ("long"), for a total of 83 amino acids (relative to the 70 of IGF-1). The consequences of these modifications are that IGF-1 LR3 retains the pharmacological activity of IGF-1 as an agonist of the IGF-1 receptor, has very low affinity for the insulin-like growth factor-binding proteins (IGFBPs), and has improved metabolic stability. As a result, it is approximately three times more potent than IGF-1, and possesses a significantly longer half-life of about 20–30 hours (relative to IGF-1's half-life of about 12–15 hours). IGF-1 LR3 (insulin-like growth factor-1 long arginine 3) is a synthetic, modified construct of insulin-like growth factor-1. Because IGF-1 LR3 does not bind to IGF-1 binding proteins very well, it remains active up to 120 times longer than standard IGF-1. This results in improved half-life for the peptide and thus increased activity. IGF-1 LR3 enhances cell division and growth, boosts fat metabolism, and increases muscle repair and hypertrophy by inhibiting myostatin. IGF-1 LR3 inhibits the movement of glucose into the body cells which facilitates fat burning and the use of fat in the body for the production of energy.
- Helps production of protein synthesis in the body
- It regulates the storage of fat and distributes it to be used for the production of energy.
- Increases lean body mass and decreases fat
- Increases the regenerative properties of the body’s nerve tissues.
- Up-regulates anti-oxidant benefits
- Helps in the development of hyperplasia in muscle cells, which lead to fuller muscle tissues
KPV
Brief Overview
Lysine-proline-valine (KPV) is a C-terminal peptide fragment of #-melanocyte stimulating hormone with potent anti-inflammatory properties. KPV is a peptide that is naturally produced in the body. It is found in the hormone alpha-MSH. It is used for inflammation, gut health and conditions such as Inflammatory Bowel Disease (IBD) and colon cancer.KPV is shown to be safe when administered orally, subcutaneously and topically. KPV is a naturally derived peptide without any notable side effects. Research has shown that KPV offers a host of benefits that speed wound healing, reduce infection and fight inflammation.
- Benefits for many inflammatory conditions
- Strengthens immune system
- May help irritable bowel diseases (IBD’s)
- Accelerated wound healing
- Accelerated injury healing
- Benefits for ulcerative colitis
- Benefits for intestinal damage
- Improves overall skin appearance
- Repairs skin barrier proteins
Larazotide
Brief Overview
Larazotide is a synthetic eight amino acid peptide that functions as a tight junction regulator and acts as a zonulin antagonist to reduce zonulin-induced increases in barrier permeability and has been associated with the redistribution and rearrangement of tight junction proteins and actin filaments to restore intestinal barrier function. It is being studied in people with celiac disease.
- Benefits for many inflammatory conditions
- Prevents breakdown of tight junctions
- May help Leaky Gut Syndrome
- Restores intestinal barrier function
- May help with limiting the movement of molecules through the intestinal wall
- May help reverse the damage caused by celiac disease
Methylene Blue
Brief Overview
Methylene blue has many anti-inflammatory and anti-oxidant properties. It has been shown to activate SIRT1, help with skin appearance, and even help with immune function. Methylene Blue has been shown to attenuate the formations of amyloid plaques and neurofibrillary tangles, and to partially repair impairments in mitochondrial function and cellular metabolism. Methylene Blue boosts mitochondrial energy and improves mood and memory. Methylene Blue shows promise in treating neurological disorders such as mild cognitive impairment, Alzheimer’s, and Parkinson’s disease.
- Stimulates glucose metabolism in conditions without oxygen and increases the amount of NAD + produced by mitochondria
- Enhances the function of cytochrome oxidase
- May mimic oxygen’s function in the mitochondria
- Functions as a powerful antioxidant
- Benefit with monoamine oxidase (MAO) inhibitor for antidepressant effects
- Neurotransmitter in the brain responsible for arousal, attention, memory and motivation
MOTS-C
Brief Overview
Mitochondrial-derived peptide (MOTS-c) is a 16-amino acid peptide encoded by mitochondrial DNA. primarily targets muscle tissue, where it restores insulin sensitivity, counteracting diet-induced and age-dependent insulin resistance. MOTS-c is a high potential candidate for chronic treatment of menopausal induced metabolic dysfunction and weight loss by regulating muscle and fat metabolism and increased energy. Recent studies have shown MOTS-c prevented ovariectomy-induced obesity and insulin resistance. MOTS-c treatment increased brown fat activation and reduced OVX-induced fat accumulation and inflammatory invasion in white adipose tissue, which contributes to the lower level of fatty acid in serum and liver. MOTS-c activates AMPK pathways to improve energy dissipation and insulin sensitivity. A blocker of AMPK pathway was found to attenuate the role of MOTS-c in the regulation of adipocyte lipid metabolism.
- Promotes lipolysis
- Fat loss by boosting mitochondrial function
- Regulates muscle and fat metabolism
- Decreases insulin resistance
- Increased GLUT4 uptake in muscle
- Increased endurance
- Improved cellular repair
- Less appetite stimulation
- Increased energy
PDA (Pentadeca Arginate)
Brief Overview
Pentadeca Arginate (PDA) is a novel synthetic peptide composed of 15 arginine residues, designed to enhance cellular repair, regeneration, and immune modulation. Originally investigated for its potential in neuroprotective and anti-inflammatory applications, PDA demonstrates a wide range of systemic benefits, particularly in supporting tissue recovery and cellular resilience. Its mechanism centers on improving mitochondrial function and promoting mitochondrial bioenergetics. PDA has been shown in early studies and anecdotal use to promote healing in both neural and musculoskeletal tissues, making it a promising agent for age-related decline, recovery from injury, and optimizing cellular health. Unlike traditional growth factors, PDA appears to exert its regenerative effects without overstimulating cell proliferation, potentially offering a safer long-term profile. In integrative and functional medicine settings, PDA is being explored for patients dealing with chronic fatigue, neuroinflammation, or degenerative conditions. It is typically administered via subcutaneous injection and is generally well tolerated.
- Supports joint health
- Protects against drug-induced damage
- Modulates inflammation
- Supports mitochondrial function
- Supports cognitive performance
- Promotes lipolysis
- Improves overall skin appearance
- Enhances tissue recovery
PE-22-28
Brief Overview
PE-22-28 is a peptide that aids in the treatment of mood, depression and cognition. PE 22-28 is a synthetic derivative of the naturally occurring protein called Spadin. It is a promising endogenous peptide with antidepressant activity. Spadin specifically blocks the TREK-1 channel. Spadin helps regulate the TREK-1 pathway in the central nervous system and also acts as a neurogenic regulator. TREK-1 (TWIK related potassium channel) receptor is a two pore potassium channel that was recently identified as a potential target to treat depression. TREK-1 receptor is primarily found in the brain region including prefrontal cortex and hippocampus, i.e., areas governing mood, memory and learning in humans. PE-22-28 binds to TREK-1 channel and blocks its activity, thereby producing mind stability and mood enhancing effects, with much more promising results than Spadin alone. PE-22-28 has been shown to induce neurogenesis after just four days, which is substantially faster than other therapies.
- Helps manage depression
- Upregulates neurogenesis in a shorter duration of time compared to antidepressant drugs premenopausal women
- Stimulates synaptogenesis
- Fewer side effects compared to antidepressant drugs
- Increases muscle function
- Helps with Post Stroke Depression (PSD)
- Helps with Neurodegenerative diseases
Pentosan Polysulfate
Brief Overview
Pentosan Polysulfate is a semi-synthetic polysulfated xylan used for the relief of Osteoarthritis. The mechanism of Pentosan Polysulfate action in osteoarthritis is multifactorial, with both stimulation of cartilage matrix synthesis and prevention of cartilage breakdown. There are also systemic effects on blood lipid and fibrinolysis that may help clear the subchondral circulation. In one study, after a series of four to six intra-articular Pentosan Polysulfate injections into knees of human volunteers, there was a significant increase in the size of the synovial fluid hyaluronan without causing any inflammation or bleeding into the joint cavity. Pentosan Polysulfate is also believed to support the healing of the interstitial cystitis (inflammation of the bladder) by providing a protective coating to the damaged bladder wall. Pentosan Polysulfate is similar in structure to the natural glycosaminoglycan coating of the inner lining of the bladder, and may replace or repair the lining, reducing its permeability.
- Improve blood flow to the sub-chondral bone under the worn cartilage
- Stimulate of cartilage matrix synthesis
- Prevent cartilage breakdown by enzymes
- Maintain the proteoglycan content in the articular cartilage
- Helps relieve bladder pain and discomfort related to interstitial cystitis
PT-141 (Bremelanotide)
Brief Overview
PT-141 (Bremelanotide) is a synthetic peptide developed from Melanotan 2 (MT-II). PT-141 is used for the treatment of erectile dysfunction or impotence in men and HSDD (hypoactive sexual desire disorder) in women. PT-141 is a peptide that was originally developed as a sunless tanning agent. It is a melanocyte stimulating hormone (MSH) that affects sexual arousal, aiding enhanced libido levels and penile erections. Unlike all PDES inhibitors, PT-141 does not target the vascular system. Instead, it acts on the nervous system via activation of neurons in the hypothalamus to increase sexual desire.
- HSDD (hypoactive sexual desire disorder) in premenopausal women
- Beneficial for low libido (male & female)
- Increase energy
- Beneficial for ED (erectile dysfunction)
- Helps enhance sexual satisfaction
- Skin pigmentation (sunless tanning agent)
Selank
Brief Overview
Selank is a heptapeptide which is a derivative of tetra-peptide Tuftsin, which the human body produces naturally. This comes with a broad range of benefits. The Institute of Molecular Genetics of the Russian Academy of Science initially synthesized Selank during the late 1990’s. Stage III clinical tests were quite successful in Russia. It is one of the latest substances used for its many anti-anxiety (anxiolytic) effects. Selank is a precursor to the tetrapeptide known as Tuftsin. This tetrapeptide can efficiently improve and transform your immune system.
- Superior learning aptitude and memory processes
- Better sensory awareness
- Improved curiosity
- Enhanced mental concentration
- Regulation of the activities of noradrenergic and serotonergic brain systems
- Decreased anxiety and stress levels
- Better antiviral functioning without any adverse side effects
- Improved cerebral energy
- Better and steady mood as well as feelings of gratification and happiness
Semax
Brief Overview
Semax is a peptide known best for its nootropic, neurogenic/neurorestorative and neuroprotective properties. It is a modified snippet of a hormone called adrenocorticotropic hormone (ACTH). Semax is the basis for a number of drugs that are used in clinical practice for the treatment of CNS diseases (ischemic brain stroke, dys-circulatory encephalopathy, optic nerve atrophy, etc.) and to enhance adaptability under extreme conditions in healthy persons. Heptapeptide SEMAX (MEHFPGP) is the analogue of ACTH (4-10) that has prolonged neurotropic activity and thus is a good candidate for medical therapy. Currently this peptide is successfully used in treatment of patients with pathologies related to brain circulation dysfunction and with different intellectualamnestic problems of the CNS. Doctors have prescribed it for many conditions like anxiety, memory improvement, ischemic events, stroke, nerve regeneration, ADHD, opioid withdrawal, and even chronic diseases such as ALS, Parkinson’s, and Alzheimer’s.
- Enhanced mental concentration
- Increased attention and short-term memory
- Increased brain BDNF levels
- Reduces breakdown of enkephalins
- Improved Non-proliferative Diabetic Neuropathy
- Can help during recovery from Stroke/Hypoxia
- Improved Glaucoma Optic Neuropathy
- Helpful in the treatment of ADHD
- Nootropic (cognitive-enhancing) effects
- Neuroprotection: may help protect the brain from various types of stress and damage
- Decreased anxiety and stress levels
Semaglutide + B6
Brief Overview
Semaglutide is a glucagon-like peptide (GLP-1) analog as an FDA approved treatment method for improving glycemic control in patients with Type 2 diabetes. It increases insulin secretion, which is good for diabetes. At higher doses, it can act on centers in the brain and help suppress appetite. Used in conjunction with lifestyle changes and a reduced-calorie diet, Semaglutide can have a very successful outcome with weight loss and lowering high blood pressure. Studies show that Semaglutide can reduce appetite, improved control of eating, and reduce food cravings in addition to improved glycemic control. Some studies show negative side effects may include nausea, diarrhea and even vomiting. The inclusion of Pyridoxine (B6) may help decrease nausea effect.
- Promotes lipolysis
- Improves blood sugar levels in adults with Type 2 diabetes
- Lowers A1C
- Cardiovascular benefits - lowers risk of cardiovascular events such as heart attacks & strokes
- Lowers BMI
- Plaque hemorrhage is reduced
- Helps pancreatic insulin release to lower glucose levels in the bloodstream
Semaglutide + LIV
Brief Overview
Semaglutide is a glucagon-like peptide (GLP-1) analog as an FDA approved treatment method for improving glycemic control in patients with Type 2 diabetes. It increases insulin secretion, which is good for diabetes. At higher doses, it can act on centers in the brain and help suppress appetite. Used in conjunction with lifestyle changes and a reduced-calorie diet, Semaglutide can have a very successful outcome with weight loss and lowering high blood pressure. Studies show that Semaglutide can reduce appetite, improved control of eating, and reduce food cravings in addition to improved glycemic control. Some studies show negative side effects may include nausea, diarrhea and even vomiting. The inclusion of LIV (Leucine, Isoleucine, Valine) the three branched-chain amino acids or BCAAs could offer potential benefits, especially in the context of preserving muscle mass during weight loss by promoting muscle protein synthesis (MPS).
- Promotes lipolysis
- Improves blood sugar levels in adults with Type 2 diabetes
- Lowers A1C
- Cardiovascular benefits - lowers risk of cardiovascular events such as heart attacks & strokes
- Lowers BMI
- Plaque hemorrhage is reduced
- Helps pancreatic insulin release to lower glucose levels in the bloodstream
- Muscle Preservation
- Protein Synthesis Support
Sermorelin Acetate
Brief Overview
Sermorelin (brand names Geref), is a peptide analogue of growth hormone-releasing hormone (GHRH) which is used as a diagnostic agent to assess growth hormone (GH) secretion for the purpose of diagnosing growth hormone deficiency. It is a 29- amino acid polypeptide representing the 1–29 fragment from endogenous human GHRH, thought to be the shortest fully functional fragment of GHRH.
- Increase in lean body mass
- Promotes lipolysis
- Increased energy
- Increased strength
- Accelerated wound healing
- Improved cardiovascular and immune function
- Improves sleep quality
- Improved bone density
- Improved skin quality and higher collagen density
- Increased IGF-1
Sirolimus
Brief Overview
Sirolimus, also known as rapamycin, is an mTOR (mechanistic target of rapamycin) inhibitor originally developed as an immunosuppressant to prevent organ transplant rejection. It works by inhibiting the mTORC1 pathway, a key regulator of cell growth, proliferation, and metabolism. Over time, sirolimus has gained considerable attention in the field of longevity and regenerative medicine due to its potential to extend lifespan and delay age-related diseases. Preclinical studies have shown that sirolimus can increase lifespan in multiple species, including mice, by improving autophagy (cellular cleanup), reducing inflammation, and optimizing metabolic function. Clinically, sirolimus has been explored for treating certain cancers, tuberous sclerosis, and vascular anomalies, and is now being evaluated for its off-label potential in anti-aging protocols. In low, intermittent doses, sirolimus may provide cellular and immune rejuvenation benefits without the immunosuppression seen at transplant-level doses. However, side effects like mouth ulcers, lipid imbalances, and delayed wound healing can occur, and use should be carefully monitored by experienced clinicians.
- Promotes autophagy
- Inhibits mTOR a key driver in cellular senescence
- Extends lifespan
- Modulates inflammation
- Supports healthy metabolic regulation and insulin sensitivity
- Potential anti-cancer properties via suppression of abnormal cell growth
SLU-PP-332
Brief Overview
SLU-PP-332 is a peptide known for its role as a REV-ERB agonist, meaning it activates REV-ERB nuclear receptors that regulate circadian rhythm, metabolism, inflammation, and mitochondrial function. Developed to explore metabolic and aging-related disorders, SLU-PP-332 is part of a growing category of compounds targeting cellular energy homeostasis and bio-rhythmic balance. By modulating the activity of REV-ERB# and REV-ERB", SLU-PP-332 helps suppress genes involved in fat storage and inflammation while boosting mitochondrial biogenesis and fatty acid oxidation. It has demonstrated the potential to reduce body fat, enhance muscle endurance, and improve metabolic efficiency—even mimicking the effects of exercise in sedentary subjects. SLU-PP-332 has also shown promise in addressing circadian rhythm disruptions, making it of interest in cases of insomnia, jet lag, and shift work fatigue. Its applications may extend to support for metabolic syndrome, obesity, and neurodegenerative conditions where inflammation and mitochondrial decline play a central role.
- Increase in lean body mass
- Promotes lipolysis
- Increased energy
- Increased strength
- Supports joint health
- Modulates inflammation
- Improved cognitive function and mood benefit
- Improves sleep quality and regulates circadian rhythm
- Enhances mitochondrial function
Tesofensine
Brief Overview
Tesofensine is a serotonin–noradrenaline–dopamine reuptake inhibitor from the phenyltropane family of drugs. Originally, Tesofensine was developed by a biotechnology company for the treatment of Alzheimer's and Parkinson's disease but was subsequently dropped from development for these applications after early trial results showed limited efficacy for treatment of these diseases. However, weight loss was consistently reported as an adverse event in the original studies, especially in overweight or obese patients thus changing the course of clinical trials towards the treatment of obesity. Tesofensine primarily acts as an appetite suppressant, but additionally can act by increasing resting energy expenditure.
- Increase in lean body mass
- Promotes lipolysis
- Increased energy
- Increase in lean body mass
- Stimulates metabolism
- Appetite suppression
- Improves sleep quality
- Decrease hemoglobin A1C and insulin levels
- Decrease triglycerides and cholesterol
Thymosin Alpha-1
Brief Overview
Thymosin Alpha-1 has been known as an excellent immune modulator. Thymosin is a small protein produced naturally by the thymus gland which stimulates the development of disease-fighting T cells. The thymus is an integral part of your immune system, where individual T-cells are made to respond to the millions of bacteria, fungi, or viruses that could invade your body. Commonly prescribed for the treatment for chronic viral diseases, Thymosin Alpha-1 has also been shown to increase innate immunity factors and help fight against harmful autoimmune processes. It is given to help control inflammation associated with chronic diseases, which can cause excess fatigue.
- Reduction in body fat
- Modulates immune function and inflammation
- Improved chronic fatigue
- Suppresses tumor growth
- Improved autoimmune function
- Anti-fungal and anti-bacterial properties
- Protects against oxidative damage
- Lyme Disease treatment
- Increases vaccine effectiveness
- Helps eliminate unhealthy cells and stop infection or cancer growth
TB-500 (TB-FRAG)
Brief Overview
TB-500 is a synthetic version of a naturally occurring peptide fragment derived from Thymosin Beta-4. It is primarily known for its role in cell migration, tissue repair, and regeneration. One of its key mechanisms of action is the regulation of actin, a protein essential for cell structure and movement. By promoting actin binding and cellular migration, TB-500 helps facilitate the repair of damaged tissues including muscles, tendons, ligaments, and skin. Unlike the full Thymosin Beta-4 molecule, TB-500 is a smaller fragment designed for enhanced systemic distribution, allowing it to travel more easily throughout the body and target multiple areas of injury. Research and clinical interest have highlighted its potential to reduce inflammation, promote angiogenesis, and accelerate healing, making it a popular option in regenerative and performance-based protocols.
- Accelerated tissue repair and regeneration
- Improved muscle recovery and reduced downtime
- Enhanced flexibility and range of motion
- Reduction in inflammation
- Support for tendon and ligament healing
- Improved endurance and performance
- Promotes angiogenesis (formation of new blood vessels)
- May help reduce scar tissue and adhesions
- Supports recovery from acute and chronic injuries
- Potential support for cardiovascular health
Tirzepatide + B6
Brief Overview
Tirzepatide is a medication used for the treatment of type 2 diabetes. Tirzepatide is given by weekly subcutaneous injection. Glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) are hormones involved in blood sugar control. Tirzepatide activates both the GLP-1 and GIP receptors and is an analogue of gastric inhibitory polypeptide (GIP), a human hormone that stimulates the release of insulin from the pancreas.This activates both the GLP-1 and GIP receptors, leading to improved blood sugar control. Studies show that Tirzepatide can reduce appetite, improved appetite regulation and reduce food cravings in addition to improved glycemic control. Some studies show negative side effects may include nausea, diarrhea and even vomiting. The inclusion of Pyridoxine (B6) may help decrease nausea effect.
- Promotes lipolysis
- Improves blood sugar levels in adults with Type 2 diabetes
- Lowers A1C
- Cardiovascular benefits - lowers risk of cardiovascular events such as heart attacks & strokes
- Lowers BMI
- Plaque hemorrhage is reduced
- Helps pancreatic insulin release to lower glucose levels in the bloodstream
Tirzepatide + LIV
Brief Overview
Tirzepatide is a medication used for the treatment of type 2 diabetes. Tirzepatide is given by weekly subcutaneous injection. Glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) are hormones involved in blood sugar control. Tirzepatide activates both the GLP-1 and GIP receptors and is an analogue of gastric inhibitory polypeptide (GIP), a human hormone that stimulates the release of insulin from the pancreas.This activates both the GLP-1 and GIP receptors, leading to improved blood sugar control. Studies show that Tirzepatide can reduce appetite, improved appetite regulation and reduce food cravings in addition to improved glycemic control. Some studies show negative side effects may include nausea, diarrhea and even vomiting. The inclusion of LIV (Leucine, Isoleucine, Valine) the three branched-chain amino acids or BCAAs could offer potential benefits, especially in the context of preserving muscle mass during weight loss by promoting muscle protein synthesis (MPS).
- Promotes lipolysis
- Improves blood sugar levels in adults with Type 2 diabetes
- Lowers A1C
- Cardiovascular benefits - lowers risk of cardiovascular events such as heart attacks & strokes
- Lowers BMI
- Plaque hemorrhage is reduced
- Helps pancreatic insulin release to lower glucose levels in the bloodstream
- Muscle Preservation
- Protein Synthesis Support
VIP (Vasoactive Intestinal Peptide)
Brief Overview
VIP, also known as vasoactive intestinal polypeptide, is a peptide hormone that is vasoactive in the intestine. VIP is a peptide of 28 amino acid residues that belongs to a glucagon/secretin superfamily, the ligand of class II G protein–coupled receptors. VIP is produced in many tissues of vertebrates including the gut, pancreas, cortex, and suprachiasmatic nuclei of the hypothalamus in the brain. VIP stimulates contractility in the heart, causes vasodilation, increases glycogenolysis, lowers arterial blood pressure and relaxes the smooth muscle of trachea, stomach and gallbladder. In humans, the vasoactive intestinal peptide is encoded by the VIP gene. It functions as a neurohormone and paracrine mediator. Therapeutically, it is often dosed nasally in patients with mold toxicity and other biotoxin illnesses. In these patients, exogenous administration can help support healthy hormone levels, works to limit inflammation, regulates the immune system, and help in the healing activity of the brain.
- Benefits for many inflammatory conditions
- May help fight against autoimmune disease
- Supports joint health
- Promotes gut health and balance
- Supports digestive system by increasing the secretion and inhibiting the absorption of intestinal luminal fluid
- May improve endocrine system by Increases insulin and glucagon secretion and Increasing blood flow in the thyroid
Zinc Thymulin
Brief Overview
Zinc and thymulin are both natural substances that play a role in the growth of hair follicles. Research has shown that they can stimulate hair growth. When combined in a foam or dropper, Zinc Thymulin can be applied to the scalp to address issues like hair loss and bald patches, while also kickstarting the anagen phase of hair growth, which is the period during which hair follicles are actively growing and the hair root is dividing rapidly. Thymulin is a nonapeptide hormone derived from the thymus gland. Early reports of thymus extract stimulating hair growth was discovered in 1986 and 2000. The activity of the hormone is reliant on the mineral Zinc, which is why it is referred to as Zinc Thymulin. Zinc thymulin may also enhance endogenous hair pigmentation by stimulating melanogenesis in grey hair.
- Improves hair growth
- Prevent hair loss
- Improves endogenous hair pigmentation
- Treatment for androgenic alopecia
- Useful for both male and female
- Can be combined with alternate hair growth protocols